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Marcus Institute Begins Study with Vitamin C to Treat COVID-19

May 26, 2020

There currently are no approved treatments for COVID-19. For those patients requiring hospitalization, standard clinical care includes therapies such as supplemental oxygen and bronchodilators to support breathing. A large subset progress to requiring mechanical ventilation.

The Marcus Institute of Integrative Health in collaboration with Jefferson’s Division of Infectious Diseases just started a study on the effectiveness of high dose infusions of Vitamin C, also known as ascorbic acid, in recently hospitalized COVID-19 patients. The study is designed with the hope of jump-starting the immune system, particularly the activity of lymphocytes, which are a crucial part of the body’s defense against viruses. The ultimate goals of the study are to slow the progression of the disease, decrease the need for mechanical ventilation, and speed up recovery time.  

This study is for hospitalized patients at Thomas Jefferson University Hospital- Center City and Methodist, diagnosed with COVID-19, who have not yet progressed to mechanical ventilation. Participants will be randomized to receive either Vitamin C treatment along with standard clinical care or standard clinical care only. It is anticipated that the study will be enrolling patients for at least the next three months. 

There is incredible excitement about this study given the possibility of helping very sick patients with a treatment that is low in toxicity, readily available, and relatively simple to administer in the hospital.